UCSF-Led Consortium Receives $26.2M to Develop Therapies for Traumatic Brain Injury

Experts Predict End to Decades-Long Deadlock in Drug Developments

A UC San Francisco-led consortium has received a $26.2 million award from the U.S. Army Medical Materiel Development Activity to develop treatments for traumatic brain injury. The Transforming Research and Clinical Knowledge in Traumatic Brain Injury Network, known as TRACK-TBI NET, will lead clinical trials of phase II drugs tested nationwide in 18 hospitals with Level 1 trauma centers. 

“Over the course of decades, there have been more than 30 clinical trials for TBI, but to date no effective drugs have been identified,” said Geoffrey Manley, MD, PhD, principal investigator of TRACK-TBI and professor of neurosurgery in the UCSF Department of Neurological Surgery. “We hope that the new research will prove more fruitful than previous TBI studies that failed to distinguish patients by objective findings obtained from imaging or blood draws.”